Anti-angiogenic effect of high doses of ascorbic acid.
9/1/2008 J Transl Med. 2008 Sep 12;6:50 Mikirova NA, Ichim TE, Riordan NH. Pharmaceutical doses of ascorbic acid (AA, vitamin C, or its salts) have been reported to exert anticancer activity in vitro and in vivo. One proposed mechanism involves direct cytotoxicity mediated by accumulation of ascorbic acid radicals and hydrogen peroxide in the extracellular…
