Pharmacokinetics of vitamin C: insights into the oral and intravenous administration of ascorbate.
3/1/2008 P R Health Sci J. 2008 Mar;27(1):7-19 Duconge J, Miranda-Massari JR, Gonzalez MJ, Jackson JA, Warnock W, Riordan NH. There is a strong advocacy movement for large doses of vitamin C. Some authors argue that the biological half-life for vitamin C at high plasma levels is about 30 minutes, but these reports are the…
A pilot clinical study of continuous intravenous ascorbate in terminal cancer patients.
12/1/2005 P R Health Sci J. 2005 Dec;24(4):269-76 Riordan HD, Casciari JJ, González MJ, Riordan NH, Miranda-Massari JR, Taylor P, Jackson JA. Case studies suggest that vitamin C, given intravenously at doses of 10-100 grams/day can improve patient well being and in some cases, reduce tumor size. While ascorbate is generally considered safe, clinical data…