Clinical Feasibility of Umbilical Cord Tissue-Derived Mesenchymal Stem Cells in the Treatment of Multiple Sclerosis
3/1/2018 J Transl Med. J Transl Med. 2018 Mar 9; 16:5 Riordan NH, Morales I, Fernández G, Allen N, Fearnot NE, Leckrone ME, Markovich DJ, Mansfield D, Avila D, Patel AN, Kesari S. Background: Multiple sclerosis (MS) is a progressively debilitating neurological condition in which the immune system abnormally erodes the myelin sheath insulating the…
Outstanding Survival and Regeneration Process by the Use of Intelligent Acellular Dermal Matrices and Mesenchymal Stem Cells in a Burn Pig Model
12/1/2010 Transplant Proc. 2010 Dec;42(10):4275-8. Mansilla E, Spretz R, Larsen G, Nuñez L, Drago H, Sturla F, Marin GH, Roque G, Martire K, Díaz Aquino V, Bossi S, Gardiner C, Lamonega R, Lauzada N, Cordone J, Raimondi JC, Tau JM, Biasi NR, Marini JE, Patel AN, Ichim TE, Riordan N, Maceira A. A pig model…
Inhibition of intracranial glioma growth by endometrial regenerative cells.
2/1/2009 Cell Cycle. 2009 Feb 15;8(4):606-10. Epub 2009 Mar 2 Han X, Meng X, Yin Z, Rogers A, Zhong J, Rillema P, Jackson JA, Ichim TE, Minev B, Carrier E, Patel AN, Murphy MP, Min WP, Riordan NH. Animal studies have demonstrated that selective tropism of mesenchymal stem cells (MSC) for glioma may be used…
Case report: effect of umbilical cord mesenchymal stem cells on immunoglobulin A nephropathy after acute renal failure
7/14/1905 Am J Transl Res. 2022; 14(7): 4855–4859 NH Riordan, RA Ambrozic, J Paz-Rodríguez. Immunoglobulin A nephropathy is an inflammatory, autoimmune condition that may lead to renal impairment in its most aggressive forms. In this case report, a 50-year-old male with acute renal failure was diagnosed with IgA nephropathy, having elevated creatinine levels (3.0 mg/dL)…
Dodging COVID-19 infection: low expression and localization of ACE2 and TMPRSS2 in multiple donor-derived lines of human umbilical cord-derived mesenchymal stem cells
7/13/1905 J Transl Med 19, 149 (2021) Hernandez JJ, Beaty DE, Fruhwirth LL, Lopes Chaves AP, Riordan NH. Background: Mesenchymal stem cells derived from human umbilical cord (hUC-MSCs) have immunomodulatory properties that are of interest to treat novel coronavirus disease 2019 (COVID-19). Leng et al. recently reported that hUC-MSCs derived from one donor negatively expressed…