Autologous stromal vascular fraction cells: a tool for facilitating tolerance in rheumatic disease.
4/1/2010 Cell Immunol. 2010;264(1):7-17. Ichim TE, Harman RJ, Min WP, Minev B, Solano F, Rodriguez JP, Alexandrescu DT, DeNecochea-Campion R, Hu X, Marleau AM, Riordan NH. Since the days of Medawar, the goal of therapeutic tolerogenesis has been a “Holy Grail” for immunologists. While knowledge of cellular and molecular mechanisms of this process has been…
Antigen-specific therapy of rheumatoid arthritis.
2/1/2008 Expert Opin Biol Ther. 2008 Feb;8(2):191-9 Ichim TE, Zheng X, Suzuki M, Kubo N, Zhang X, Min LR, Beduhn ME, Riordan NH, Inman RD, Min WP. Background: Immunotherapy offers the promise of antigen-specific suppression of pathological immune responses in conditions such as autoimmunity and organ transplantation. Substantial advances have been made in recent years…
A novel method of modifying immune responses by vaccination with lipiodol-siRNA mixtures.
1/1/2006 J Transl Med. 2006 Jan 3;4:2 Ichim TE, Popov IA, Riordan NH, Izadi H, Zhong Z, Yijian L, Sher S, Oleinik EK. The dendritic cell (DC) possesses the ability to stimulate both T helper 1 (Th1) and Th2 responses depending on activation stimuli. Although it is known that chemically or genetically modified DC can…