A review of therapeutic effects of mesenchymal stem cell secretions and induction of secretory modification by different culture methods.
10/1/2014 J Transl Med. 2014 Oct 11;12:260 Madrigal M, Rao KS, Riordan NH. The mesenchymal stem cell (MSC) is being broadly studied in clinical trials. Contrary to the early paradigm of cell replacement and differentiation as a therapeutic mechanism of action, evidence is mounting that the secretions of the cells are responsible for their therapeutic…