Therapeutic use of Aldara in chronic myeloid leukemia.
1/1/2007 J Transl Med. 2007 Jan 25;5:4 Marleau AM, Lipton JH, Riordan NH, Ichim TE. The potent clinical responses seen in patients with chronic myeloid leukemia (CML) after administration of donor-specific lymphocytes, as well as the correlation between the presence of antigen specific T cells and prolonged remission in these patients, suggests a role for…
Intravenous vitamin C as a chemotherapy agent: a report on clinical cases.
6/1/2004 P R Health Sci J. 2004 Jun;23(2):115-8 Riordan HD, Riordan NH, Jackson JA, Casciari JJ, Hunninghake R, González MJ, Mora EM, Miranda-Massari JR, Rosario N, Rivera A. A series of seven cases are presented in which intravenous vitamin C has been used as antineoplastic agent in the treatment of different types of cancers. The…
Integrative medicine: a paradigm shift in medical education and practice.
12/1/2000 P R Health Sci J. 2000 Dec;19(4):389-92 González MJ, Miranda-Massari JR, Mora EM, Cruzado NA, Jiménez I, Rosa M, Matos Vera MI, Santiago C, Román-Eyxarch MI, Rodríguez JR, Pérez Cortés C, Riordan NH, Riordan HD, Ricart CM. The use of alternative/complementary medicine has been increasing considerably. Conventional medicine must begin to address issues related…
The paradoxical role of lipid peroxidation on carcinogenesis and tumor growth: a commentary.
6/1/1996 Med Hypotheses. 1996 Jun;46(6):503-4 González MJ, Riordan NH. Lipid peroxidation has been shown to both enhance carcinogenesis and to have an anticarcinogenic effect. This paradox is of great relevance to the fields of free radical biology, biochemistry, pathology, nutrition and oncology among others and needs to be addressed. A proper understanding of this issue…
Intravenous Ascorbate As A Tumor Cytotoxic Chemotherapeutic Agent
3/1/1995 Med Hypotheses. 1995 Mar;44(3):207-13 Riordan NH, Riordan HD, Meng X, Li Y, Jackson JA. Ascorbic acid and its salts (AA) are preferentially toxic to tumor cells in vitro and in vivo. Given in high enough doses to maintain plasma concentrations above levels that have been shown to be toxic to tumor cells in vitro,…
Improved Microplate Fluorometer Counting of Viable Tumor and Normal Cells
5/1/1994 Anticancer Res. 1994 May-Jun;14(3A):927-31 Riordan HD, Riordan NH, Meng X, Zhong J, Jackson JA. An improved method has been developed to count cells in situ based on the measurement of esterase activity with carboxyfluorescein diacetate. This sensitive, semiautomated microplate fluorometer assay was able to estimate viable cell numbers over a range of 5 x…