Nutraceutical augmentation of circulating endothelial progenitor cells and hematopoietic stem cells in human subjects.
4/1/2010 J Transl Med. 2010 Apr 8;8:34 Mikirova NA, Jackson JA, Hunninghake R, Kenyon J, Chan KW, Swindlehurst CA, Minev B, Patel AN, Murphy MP, Smith L, Ramos F, Ichim TE, Riordan NH. The medical significance of circulating endothelial or hematopoietic progenitors is becoming increasing recognized. While therapeutic augmentation of circulating progenitor cells using G-CSF…
Anti-angiogenic effect of high doses of ascorbic acid.
9/1/2008 J Transl Med. 2008 Sep 12;6:50 Mikirova NA, Ichim TE, Riordan NH. Pharmaceutical doses of ascorbic acid (AA, vitamin C, or its salts) have been reported to exert anticancer activity in vitro and in vivo. One proposed mechanism involves direct cytotoxicity mediated by accumulation of ascorbic acid radicals and hydrogen peroxide in the extracellular…