Cytotoxicity of ascorbate, lipoic acid, and other antioxidants in hollow fibre in vitro tumours.
6/1/2001 Br J Cancer. 2001 Jun 1;84(11):1544-50 Casciari JJ, Riordan NH, Schmidt TL, Meng XL, Jackson JA, Riordan HD. Vitamin C (ascorbate) is toxic to tumour cells, and has been suggested as an adjuvant cancer treatment. Our goal was to determine if ascorbate, in combination with other antioxidants, could kill cells in the SW620 hollow…
Intravenous Ascorbate As A Tumor Cytotoxic Chemotherapeutic Agent
3/1/1995 Med Hypotheses. 1995 Mar;44(3):207-13 Riordan NH, Riordan HD, Meng X, Li Y, Jackson JA. Ascorbic acid and its salts (AA) are preferentially toxic to tumor cells in vitro and in vivo. Given in high enough doses to maintain plasma concentrations above levels that have been shown to be toxic to tumor cells in vitro,…
Improved Microplate Fluorometer Counting of Viable Tumor and Normal Cells
5/1/1994 Anticancer Res. 1994 May-Jun;14(3A):927-31 Riordan HD, Riordan NH, Meng X, Zhong J, Jackson JA. An improved method has been developed to count cells in situ based on the measurement of esterase activity with carboxyfluorescein diacetate. This sensitive, semiautomated microplate fluorometer assay was able to estimate viable cell numbers over a range of 5 x…