Comparison of Cost and Potency of Human Mesenchymal Stromal Cell Conditioned Medium Derived from 2- and 3-Dimensional Cultures.

8/1/2023 Bioengineering (Basel, Switzerland), 10(8), 930. Madrigal, M., Fernández, P. L., Lleonart, R., Carreño, L., Villalobos Gorday, K. A., Rodríguez, E., de Cupeiro, K., Restrepo, C. M., Rao, K. S. J., & Riordan, N. H. Mesenchymal stromal cell (MSC)-derived products, such as trophic factors (MTFs), have anti-inflammatory properties that make them attractive for cell-free treatment….

The effects of vitamin C on the multiple pathophysiological stages of COVID-19

12/1/2021 Life (Basel). 2021 Dec 3;11(12):1341 Miranda-Massari JR, Toro AP, Loh D, Rodriguez JR, Borges RM, Marcial-Vega V, Olalde J, Berdiel MJ, Riordan NH, Martinez JM, Gil A, Gonzalez MJ. Currently available anti-viral drugs may be useful in reducing the viral load but are not providing the necessary physiological effects to reduce the SARS-CoV-2 complications…

Dodging COVID-19 infection: low expression and localization of ACE2 and TMPRSS2 in multiple donor-derived lines of human umbilical cord-derived mesenchymal stem cells

7/13/1905 J Transl Med 19, 149 (2021) Hernandez JJ, Beaty DE, Fruhwirth LL, Lopes Chaves AP, Riordan NH. Background: Mesenchymal stem cells derived from human umbilical cord (hUC-MSCs) have immunomodulatory properties that are of interest to treat novel coronavirus disease 2019 (COVID-19). Leng et al. recently reported that hUC-MSCs derived from one donor negatively expressed…