Case report of non-healing surgical wound treated with dehydrated human amniotic membrane.
7/1/2015 J Transl Med. 2015 Jul 24;13:242 Riordan NH, George BA, Chandler TB, McKenna RW. Introduction: Non-healing wounds can pose a medical challenge as in the case of vasculopathic venostasis resulting in a surgical ulcer. When traditional approaches to wound care fail, an amniotic patch (a dehydrated tissue allograft derived from human amnion) can function…
A review of therapeutic effects of mesenchymal stem cell secretions and induction of secretory modification by different culture methods.
10/1/2014 J Transl Med. 2014 Oct 11;12:260 Madrigal M, Rao KS, Riordan NH. The mesenchymal stem cell (MSC) is being broadly studied in clinical trials. Contrary to the early paradigm of cell replacement and differentiation as a therapeutic mechanism of action, evidence is mounting that the secretions of the cells are responsible for their therapeutic…