Killing Breast Cancer Stem Cells
The scientists proved that they were able to expand cancer stem cells based on cell characteristics and ability of the cells to induce tumor growth when administered to animals.
November 29, 2009
The scientists proved that they were able to expand cancer stem cells based on cell characteristics and ability of the cells to induce tumor growth when administered to animals.
In the study, fat mesenchymal stem cells were isolated from rats and tested for ability to promote healing of the endothelium, which is the lining of the blood vessels.
The study demonstrated efficacy in the treated patients based on increase cardiac muscle contraction ability as compared to patients that had bypass surgery but did not receive stem cells.
Mice that received the artificially generated liver cells, but not control mice, had a recovery in production of liver enzymes.
In the last 2 decades studies have been showing that organs such as the heart, brain and kidney have "endogenous stem cells" that are capable of creating a certain, albeit small, degree of regeneration after injury.
Mice were treated with mouse mesenchymal stem cells and mouse hematopoietic stem cells that were genetically engineered using lentiviruses.
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